联系人 Ms. Jennifer
No.3 South Changjiang Street Huanggu District, Shenyang, Liaoning
Phthalic anhydride is a versatile intermediate in organic chemistry, in part because it is bifunctional and cheaply available. It undergoes hydrolysis and alcoholysis. Hydrolysis by hot water forms ortho-phthalic acid. This process is reversible: Phthalic anhydride re-forms upon heating the acid above **0 °C.
Hydrolysis of anhydrides is not typically a reversible process. However, phthalic acid is easily dehydrated to form phthalic anhydride due to the creation of a thermodynamically favorable *-membered ring.
Organic synthesis
Phthalic anhydride is a precursor to a variety of reagents useful in organic synthesis. Important derivatives include phthalimide and its many derivatives. Chiral alcohols form half-esters (see above), and these derivatives are often resolvable because they form diastereomeric salts with chiral amines such as brucine. A related ring-opening
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