Zhanshan Road 496 Wuchang District Wuhan,Wuhan,Hubei,China
Description
Pioglitazone Hydrochloride is the hydrochloride salt preparation of Pioglitazone, a specific ligand of PPAR-γ (peroxisome proliferator-
activated receptor-γ). Pioglitaze is a thiazolidinedione compound described to produce antiinflammatory and antiarteriosclerotic
effects. Pioglitazone is demonstrated to prevent L-NAME-induced coronary inflammation and arteriosclerosis and to suppress
increased TNF-α mRNA produced by aspirin-induced gastric mucosal injury. Pioglitazone Hydrochloride is an activator of PPAR γ.
Specifications
TESTS |
SPECIFICATIONS |
RESULTS |
Description |
White to off-white powder |
White powder |
Identification |
IR/ HPLC |
Complies |
Residue On Ignition |
NMT 0.2% |
0.05% |
Heavy Metals |
NMT 20ppm |
LESS THAN 10ppm |
Loss On Drying |
NMT 0.5% |
0.32% |
Related Substances (By HPLC) Single Impurity Total Impurity |
NMT 0.5% NMT 1.0% |
0.06% 0.2% |
Assay (By HPLC) |
98.0-102.0% |
99.8% |