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Povidone
iodine(Povidone-I)
Product name: PVP-I(PVP-Iodine/Povidone-I)
Chemical Name: Complex of PVP with iodine
CTFA Nomenclature: PVP-Iodine
CAS No.: 25655-41-8
Molecular formula: (C6H9NO)n·xl
Physical Properties: exists as yellow-brown or red-brown formless
powder having slightly special smell.It can dissolve in water and
alcohol,not in diethylethe or choroform.It is stable complex with
no irritation which can sterilize bacterial,virus,fungus
effectively.It is the first-selected iodine-containing
microbicide.
Specification:
Loss on drying:≤8.0%
Residue on ignition:≤0.1%
Heavy metal: ≤20PPM
Arsenic: ≤1.5PPM
Nitrogen:≤9.5-11.5%
Iodine ion:≤6.6%
Available iodine: 9.0-12.0%
PH(10% in water):1.5-5.0
Application:
.Bactericide,virucide,fungicide or local anticeptic in surgical
serubs or
for other rapcutical purposes and protect patient
from infection.
.microbicide for kitchen utensils in family.
.microbicide for food and feed industry.
.microbicide and disease-protector for animal.
.PVP-I was accepted into USP26 & USP28 editor and selected
firstly as iodine-containing bactericide and disease-protector in
the developed countries.
Povidone Iodine
Solution
Physical property:Red brown liqiud
Application:
Povidone-iodine (PI, Betadine) is routinely used as a preoperative
topical antiseptic in cataract surgery as it has been shown to
reduce the incidence of postoperative endophthalmitis. However, the
concentration used clinically is variable. In vitro studies have
shown that PI is paradoxically more effective at lower
concentration. This study was undertaken to determine if this
effect was reproducible in vivo.
Methods:
Aprospective randomised double blind study was carried out in the
ophthalmic theatre in a district general hospital. 105 patients
attending for routine cataract surgery were randomly allocated to
have their conjunctival fornices irrigated preoperatively with
either PI 1% (group A) or PI 5% (group B). Conjunctival swabs were
taken, in identical fashion, both before and 1 minute after
irrigation. The number and species of bacterial colonies cultured
from each swab was counted. The difference in the median number of
bacterial colonies from pre-irrigation to post-irrigation cultures
was then compared between the groups.
Packing: in 25kg coloured drum, or 1000ml bottle and in
cartons.
500ml/Bottle
10%; 500ml/Bottle 5%
Packaging and storage: Preserve in tight, light-resistant
containers.
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