Sulfo DBCO-PEG*-Maleimide is a water-soluble, sulfhydryl-reactive
reagent that enables simple and efficient incorporation of DBCO
moiety onto cysteine-containing peptides or other thiol-containing
molecules. The hydrophilic sulfonated spacer arm greatly improves
water solubility of DBCO derivatized molecules, in many cases
making it completely soluble in aqueous media. The hydrophilic PEG
spacer arm improves labeling efficiency and provides a long and
flexible connection.