联系人 Andrew
Shanghai, Shanghai
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TRF1 Background: Telomeric repeat binding
factor 1 (TERF1, PIN2, TRF1, TRBF1) and 2
(TERF2, TRF2, TRBF2) are present at telomeres
throughout the cell cycle where they regulate telomerase by
acting in cis to limit the elongation of individual
chromosome ends . Telomerase adds hexameric repeats of
5'-TTAGGG*3 'to the ends of chromosomal DNA. This
telomerase enzyme plays an influential role in cellular
immortalization and cellular senescence. TRF1 negatively
regulates telomere elongation, while TRF2 protects the
chromosome ends by inhibiting end- to-end fusions.
Down-regulation of TRF expression in tumor cells may
contribute to cell immortalization and malignant
progression. Product Information: ① Sample linear regression with the expected concentration of the correlation coefficient R is over 0.*5 ② Intra-assay: CV <9% Intra-assay: CV <*2% ③ sample: human's serum, blood plasma, and other related tissue Liquid ④ Quantitative determination kit for [TRF1] Antigen (ELISA) ● NOTE: The product information only as reference, The delivery instruction is taken as final this product information. If you want to know product of chinese name, please email: *@******************** |
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| 国家: | China |
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