Patent
Number：ZL*1 *****3.8
***********6.0
***********0.6 CE 1)This
product is a convenient hand-held devices,which can direct gene
transfer rang in situ.
2)The adjustable press of helium drives the metal-powder
particles prepacked with DNA, RNA or some other substance in the
interior of a small nylon tube into the inside of cells.
3)Compared with other gene delivery systems it has being a safe,
convenient, efficient of the advantages.
4)It can be commonly used by cells of different kinds.
5)The help of a small amount of DNA and some other
cells,multi-material microcarriers import can gointly be carried
out.
6)It is able to transport large pieces of DNA and make the target
gene have many cells transferred and eligible for transformation
both outside and inside.
7)It makes the
operation of transgenic work become more flexible, simple.
8)Radioactivity Institute of Academy Military Medical Sciences
carries out research work with this device and has achieved very
good results.
9)As published in "Biotechnology Communications" in ***1 IV was
"gene gun-occlusive disease in the rat gene therapy applications."
Another article was published by Shanghai Medical school
of Fudan University "Scandinavian Journal of Immunology,"
(***3,*8; ******7): “gene gun-mediated DNA vaccine T Helper2
through immunization against hepatitis B surface antigen with CpG
motif oligonucleotide Gly Coinjection changes in T helper 1
immune（T Helper 2 Immunity to Hepatitis B
Surface Antigen Primed by Gene-Gun-Mediated DNA Vaccination can be
Shifted Towards T helper 1 Immunity by Codelivery of CpG
Motif-Containing
Oligodeoxynucleotides）”etc。
Features
1)light weight,easy to use
2)Standard Configuration:a special gas valve and hoses,plus sample
devices,cutting machine.
3)Optional to buy:a specially-made nylon tube *0Feet/bag,metal
Microcarriers(power)0.**1.5µm or 1.**3.0µm
Main technical parameters
and application FactorSJ***0 Protable Gene GunExperimental conditionsIn situ, in vitro, in vivo, from the
bodyTarget region（small）2cm2Pressure range0.**5MPaTarget typeAnimals: any organization (skin,organs) exposure to gene
gun；cells, explant and organ
culturePlants: Field and greenhouse use, plant cell
culture and explant, yeast, bacteria, other microbesVoltage9V( capable of firing ***0 times)GasHeliumMetal particelΦ0.**1.6μm（common
Φ1.6 μm）
