Hirudin

详情

Hirudin is a naturally occurring peptide that is derived from the salivary glands of medicinal leeches. It is widely recognized for its potent anticoagulant properties. The main function of hirudin is to inhibit thrombin, it is an enzyme involved in blood clotting. By binding to thrombin directly, hirudin prevents its interaction with fibrinogen, thereby preventing the formation of fibrin, a critical component of blood clots. This function mechanism makes hirudin an extremely effective as anticoagulant. So hirudin has various application in medicine. It has been utilized in cardiovascular procedures, such as angioplasty and coronary artery bypass grafting, to prevent unwanted blood clotting during surgery. Hirudin is also applied in the treatment of thrombotic disorders, such as deep vein thrombosis and pulmonary embolism, where it helps dissolve existing blood clots and prevent further clot formation. Hirudin offers a natural alternative to traditional drugs like . In addition to its anticoagulant effects, hirudin possesses anti-inflammatory and vasodilatory properties. These properties contribute to its potential therapeutic applications in conditions such as ischemia-reperfusion injury, arterial thrombosis, and microvascular disorders.