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Dermatology Laser Treatment
Background: Minimally invasive techniques such as endovenous laser
therapy, radiofrequency ablation, and ultrasoundguided foam
sclerotherapy are widely used in the treatment of lower extremity
varicosities. These therapies have not yet been compared with
surgical ligation and stripping in large randomized clinical
trials.
Methods: A systematic review of Medline, Cochrane Library, and
Cinahl was performed to identify studies on the effectiveness of
the four therapies up to February ***7. All clinical studies (open,
noncomparative, and randomized clinical trials) that used
ultrasound examination as an outcome measure were included. Because
observational and randomized clinical trial data were included,
both the Meta-analysis Of Observational Studies in Epidemiology
(MOOSE) and Quality Of Reporting Of Meta-analyses (QUORUM)
guidelines were consulted. A random effects meta-analysis was
performed, and subgroup analysis and meta-regression were done to
explore sources of between-study variation.
Results: Of the **9 retrieved studies, *4 (*3.8%) were eligible and
assessed *2, **0 limbs. Average follow-up was *2.2 months. After 3
years, the estimated pooled success rates (with *5% confidence
intervals [CI]) for stripping, foam sclerotherapy, radiofrequency
ablation, and laser therapy were about *8% (*0%**4%), *7%
(*9%**4%), *4% (*5%**0%), and *4% (*7%**8%), respectively. After
adjusting for follow-up, foam therapy and radiofrequency ablation
were as
Effective as surgical stripping (adjusted odds ratio [AOR], 0.*2
[*5% CI, *0.*1 to 0.*5] and 0.*3 [*5% CI, *0.*9 to 1.*4],
respectively). Endovenous laser therapy was significantly more
effective compared with stripping (AOR, 1.*3; *5% CI, 0.***1.*7),
foam therapy (AOR, 1.*2; *5% CI, 0.***1.*5), and radiofrequency
ablation (AOR, 0.*1; *5% CI, 0.***1.*7).
Conclusion: In the absence of large, comparative randomized
clinical trials, the minimally invasive techniques appear to be at
least as effective as surgery in the treatment of lower extremity
varicose veins.
Lower-extremity venous insufficiency is a common medical condition
and occurs in about *5% of men and *5% of women. The effect of
venous insufficiency on patients\' health-related quality of life
(HRQOL) is substantial and comparable with other common chronic
diseases such as arthritis, diabetes, and cardiovascular disease.
In ***5 the overall cost associated with deep or superficial venous
insufficiency, or both, was about 2.5% of the total health care
budget in France and Belgium.
The treatment of varicose veins alleviates symptoms and, hopefully,
reduces the complication rate of venous insufficiency. The
traditional gold standard in the treatment of varicosity of great
saphenous veins (GSVs) is a high ligation at the saphenofemoral
junction (SFJ), followed by stripping; Conventional treatment of
small saphenous veins.
With different kinds accessories, such as flexile fiber, handpeices
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