SB**2,**1 is an opioid receptor ligand which is a potent and
selective antagonist for the nociceptin receptor (ORL1), several
times more potent than the older drug J**3,**7.[1] It does not have
analgesic effects in its own right, but prevents the development of
hyperalgesia,[2] and also shows antidepressant effects in animal
studies.[3]
Systematic (IUPAC) name
(5S,7S)7{[4(2,6dichlorophenyl)piperidin1yl]methyl}1methyl6,7,8,9tetrahydro5Hbenzo[7]annulen5ol
Clinical data
Legal status
Identifiers
CAS number ********2
ATC code
PubChem CID *******2
IUPHAR ligand ***3
ChEMBL CHEMBL*****9
Synonyms SB**2,**1
Chemical data
Formula C*4H*9Cl2NO
Mol. mass **8.**8 g/mol