The Dengue IgG/IgM Ab Rapid Test is a qualitative membrane-based
immunoassay for the detection of Dengue antibodies in serum or
plasma. This test consists of two components, an IgG component and
an IgM component. In the IgG component, antihuman IgG is coated in
IgG test line region. During testing, the specimen reacts with
Dengue antigen-coated particles in the test cassette. The mixture
then migrates upward on the membrane chromatographically by
capillary action and reacts with the anti-human IgG in IgG
test line region. If the specimen contains IgG antibodies to
Dengue, a colored line will appear in IgG test line region. In the
IgM component, antihuman IgM is coated in IgM test line region.
During testing, the specimen reacts with anti-human IgM.
Dengue IgM antibodies, if present in the specimen, reacts with the
anti-human IgM and the Dengue antigen-coated particles in the
test cassette, and this complex is captured by the anti-human IgM,
forming a colored line in IgM test line region. Therefore, if the
specimen contains Dengue IgG antibodies, a colored line will appear
in t IgG test line region. If the specimen contains Dengue IgM
antibodies, a colored line will appear in IgM test line region. If
the specimen does not contain Dengue antibodies, no colored line
will appear in either of the test line regions, indicating a
negative result
