离岸价格
获取最新报价15 ~ 20 / Acre ( Negotiable )
|Minimum Order
位置:
-
最小订单价格:
最小订单:
1
包装细节:
5kg/tin
交货时间:
5-10days
供应能力:
-
付款方式:
T/T, L/C, D/A, D/P, Western Union, Money Gram, PayPal
联系人 Mr. Janson
Jinzhai, Hefei, Anhui
Heparin is a sulfated nature glycosaminoglycan of mixed composition, released by mast cells and by blood basophiles in many tissues of human body and mammal body, and having potent anticoagulant properties, existing in the form of proteoglycan unit, and its chemical structure formed by connection of D-glucopyranuronic acid and D-glucosamine by turns, molecular weight distribution ***0~****0, average molecular weight ****0.
Clinical
heparin is obtained from the mucosa of small intestine of porcine
origin by purification, usually in the form of heparin sodium and
heparin calcium, mainly heparin sodium.
Usage
Heparin has potent anticoagulant and antithrombotic properties,
i.e. inhibiting Xa and IIa. Heparin binds to the enzyme inhibitor
antithrombin III (ATIII) causing a conformational change that
result in its activation through an increase in the flexibility of
its reactive site loop. The activated AT then inactivates thrombin
and other proteases involved in blood clotting, most notably factor
Xa. So it can be used in both of inside and outside body. Except
for its anticoagulant and antithrombotic properties, heparin also
has a lot of biological functions such as hypolipidemic, anti-
atherosclerosis, anti-smooth muscle cells proliferation(SMC),
antiphlogistic, antianaphylaxis, anti-virus and anticancer
etc.. So heparin is used widely in medicine and also has well
therapeutic effectiveness to many diseases. Excepting for directly
using in clinical hypolipidemic and anti- atherosclerosis, heparin
also is the raw material for producing low molecular weight heparin
and the kinds of heparin derivative
medicine.
Heparin can be used for:
1. Prevention of thrombus: during those surgical operation
such as displacement of hip joint, knee joint and percutaneous
coronary intervention (PCI), heparin can be used to prevent
thrombus mainly including deep venous thrombosis and lung
thrombosis;
2. Prevention and treatment of thrombotic disease: such as
miocardial infarction, unstable angina and apoplexy and so
on.
3. Treatment of disseminated intravascular coagulation (DIC)
caused by all kinds diseases.
4. Anticoagulant outside body: hematodialysis, blood bank,
extracorporeal circulation, blood sample and intravascular stent
and so on.