Alkyne-PEG*-Maleimide enables simple and efficient incorporation of
terminal alkyne group onto antibodies, cysteine-containing peptides
and other thiol-containing molecules. The hydrophilic polyethylene
glycol (PEG) spacer arm imparts solubility in aqueous buffers, and
provides a long and flexible connection that minimizes steric
hindrance involved with ligation to complementary azide-containing
molecules.