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Rapamycin (Sirolimus)
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Rapamycin (Sirolimus)
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Rapamycin (Sirolimus)

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型号:

ANC00370

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联系人 Ms. Amy

Five Greentree Centre, 525 Route 73 North, Marlton, New Jersey

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Rapamycin, a macrolide compound obtained from Streptomyces hygroscopicus, is a potent and specific mTOR inhibitor (IC*0: 0.1 nM in HEK**3 cells).  Rapamycin is a macrolide antibiotic that has been studied as a potential anticancer agent. It binds to FK**6 binding proteins (FKBPs) to form a complex that inhibits mammalian targets of rapamycin (mTOR). Rapamycin also blocks p*0 S6 kinase activation by interleukin*2 and thereby inhibits proliferation of T cells. It induces differentiation of human pluripotent stem cells (hPSCs) to mesendoderm and blood progenitor cells.

国家: USA
型号: ANC00370
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位置: -
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付款方式: T/T
產品組 : Inhibitors

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